1992 · FINDING
CITEDPotency Study
10x greater potency than IGF-1 due to reduced IGFBP binding
⚠ RESEARCH USE ONLY · NOT FDA-APPROVED FOR HUMAN USE · NOT MEDICAL ADVICE
MUSCLE & RECOVERYRESEARCH
IGF-1 DES.
The Targeted Muscle Growth Peptide
AKA · IGF-1 DES(1-3) · Des(1-3)IGF-1 · DES IGF
MUSCLE & RECOVERYHEALINGNASAL SPRAYSINTRAMUSCULARSUBCUTANEOUS
Truncated IGF-1 variant that's 10x more potent than regular IGF-1. Popular for localized muscle growth when injected directly into target muscles.
~20-30 minutes
Half-life
2
Citations
3
Routes
3
Categories
Store
Storage
55
Popularity
AT A GLANCE.
§ 01 · TL;DRTHE QUICK READ.
Truncated IGF-1 variant that's 10x more potent than regular IGF-1. Popular for localized muscle growth when injected directly into target muscles.
Supercharged version of IGF-1 that promotes muscle cell growth and division, especially effective when injected locally.
Very short half-life. Must be used immediately post-workout for best results.
WHAT IT MIGHT HELP WITH.
1
10x more potent than regular IGF-1
2
Localized muscle growth (site injection)
3
Hyperplasia (new muscle cell creation)
4
Enhanced recovery
5
Does not require binding proteins
HOW IT WORKS.
§ 02 · MECHANISMSupercharged version of IGF-1 that promotes muscle cell growth and division, especially effective when injected locally.
Des(1-3)IGF-1 lacks the first 3 amino acids of IGF-1, reducing binding protein affinity and increasing bioavailability. Activates IGF-1R with ~10x potency of intact IGF-1.
WHO IT'S FOR
- ✓Advanced bodybuilders
- ✓Those wanting localized muscle development
- ✓Athletes in recovery
- ✓Experienced peptide users
WHO SHOULD AVOID
- ✕Beginners to peptides
- ✕Diabetics
- ✕History of cancer
- ✕Pregnant/nursing
- ✕Under 25 years old
THE RESEARCH.
§ 03 · 2 STUDIES1995 · FINDING
CITEDMuscle Cell Proliferation
Induced satellite cell activation and myoblast proliferation
DOSING PROTOCOL.
§ 04 · DOSINGTYPICAL RANGE
Very short half-life. Must be used immediately post-workout for best results.
20-50mcg per injection site, post-workout
FREQUENCY
Most-cited schedule
Post-workout, injected bilaterally into trained muscles
ROUTES
Delivery methods
INTRAMUSCULAR · SUBCUTANEOUS · NASAL
HALF-LIFE
Steady state drives frequency
~20-30 minutes
STORAGE
Protect from light, refrigerate
Store lyophilized at
⚠ NOTE
These are reported protocols from research literature and practitioner accounts, not prescriptions. No FDA-approved human dose exists for research compounds. Anyone using IGF-1 DES should work with a qualified physician and source from a supplier providing third-party COAs.
FORMS AVAILABLE
- · Intramuscular injection (into target muscle)
- · Subcutaneous injection
⚠ RESEARCH INFORMATION ONLY · NOT MEDICAL ADVICE
COMMON STACKS.
§ 05 · COMBINATIONSSIDE EFFECTS & RISKS.
§ 06 · SAFETY•
Hypoglycemia
Common · moderate
Have carbs available
·
Injection site swelling
Common · mild
·
Joint pain
Occasional · mild
·
Headache
Occasional · mild
WHERE TO SOURCE
§ 07 · SUPPLIERPEAK LAB
PEPTIDES
PEPTIDES
SUPPLIER OF RECORD · 12 BATCHES PASSED
IGF-1 DES is not currently stocked by our vetted supplier. If you're researching it, verify any source with a third-party COA — our full sourcing guide covers what to look for.
COMMON QUESTIONS.
§ 08 · FAQWhy inject into the muscle I trained?
IGF-1 DES has localized effects. Injecting into the trained muscle maximizes growth in that specific area.
What's hyperplasia?
Creation of new muscle cells, as opposed to hypertrophy (enlarging existing cells). IGF-1 DES may promote both.
Why is it so unstable?
The truncated structure that makes it potent also makes it degrade quickly. Always use fresh and store properly.
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