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Melanotan II

Also known as: MT-2, MT2, Barbie Drug

The Multi-Effect Tanning Peptide

Potent melanocortin peptide that produces tanning, increases libido, and reduces appetite. More side effects than MT-1 but stronger multi-system effects.

Research✨ Skin & Anti-Aging ❤️ Sexual Health 👃 Nasal Sprays👃 Also available as nasal spray

How It Works

Simple Explanation

Activates multiple melanocortin receptors causing tanning, increased sexual arousal, and appetite suppression.

Technical Details

Non-selective melanocortin agonist affecting MC1R (tanning), MC3R/MC4R (sexual function, appetite), producing broad physiological effects.

Pharmacokinetics & Storage

Half-Life

~1 hour

Duration in circulation

Storage Requirements

Before use: Store lyophilized at -4°F to 39°F (-20°C to 4°C)

After reconstitution: Use within 4 weeks when refrigerated

Very light sensitive. Reconstitute with bacteriostatic water.

Benefits

Rapid, deep tanning
Significantly increased libido (both sexes)
Appetite suppression
May improve erectile function
UV protection via melanin increase

Potential Side Effects

Nausea

Very common initially

Start with low doses

moderate

Facial flushing

Very common

mild

Spontaneous erections

Common in men

mild

Mole darkening

Common

Requires monitoring

mild

Fatigue/yawning

Common

mild

Research Highlights

Sexual Function (2000)

Significant improvement in erectile function and female arousal

View Study

Tanning Efficacy (1999)

Produced tanning in all skin types with minimal UV exposure

View Study

Melanotan II Safety Review (2023)

Updated safety review documents side effect profile and monitoring recommendations

View Study

Frequently Asked Questions

Why is it called 'Barbie Drug'?

Media nickname due to its tanning and libido effects. It's a research peptide, not a recreational drug.

How do I minimize nausea?

Start with very low doses (0.1-0.25mg), take before bed, and slowly increase over 1-2 weeks.

Will my tan be permanent?

No, but MT-2 tans last longer than sun tans. Maintenance doses help preserve color.

Who Is It For

Those wanting rapid tanning
Low libido (both sexes)
Appetite control seekers
Fair-skinned individuals wanting UV protection

Who Should Avoid

History of melanoma
Cardiovascular conditions
Pregnant/nursing
Those with many moles
History of priapism

Research Dosing Protocols

Common Research Protocol

Loading: 0.25-0.5mg daily for 1-2 weeks. Maintenance: 0.5-1mg 1-2x weekly

Administration Frequency (per studies)

Daily during loading, then weekly maintenance

Delivery Methods

subcutaneousnasal

👃 This peptide is also available in nasal spray form from select suppliers.

Available Forms

• Subcutaneous injection
• Nasal spray

💡 Start very low (0.1mg) to assess tolerance. Nausea common initially.

⚠️ Not Medical Advice: Dosing information is compiled from published research and clinical studies for educational purposes only. This is not a recommendation. All peptide research should be conducted by qualified professionals in controlled research environments. Consult a healthcare provider before considering any protocol.

Where to Buy

Looking for quality Melanotan II? Check our vetted suppliers.

View Trusted Suppliers

Related Peptides

☀️Melanotan I

FDA-approved (as Scenesse) for EPP patients, this melanocortin peptide stimulates natural melanin production for tanning and UV protection without sun exposure.

❤️PT-141

FDA-approved for female sexual dysfunction. Works on the brain (not blood flow) to increase desire.

⚠️ Important Disclaimer

This information is for educational purposes only and is not medical advice. Many peptides discussed are research compounds not approved for human use by the FDA. Always consult with a qualified healthcare provider before starting any peptide protocol. PepGains does not sell peptides and is not responsible for how this information is used. All timeline and efficacy information is based on published research and clinical trials - individual results may vary significantly.