Quick Take
Semax is a Russian-developed nootropic peptide that's been prescribed there for decades. It boosts BDNF (brain fertilizer), enhances focus, and may help with anxiety and depression. Administered as a nasal spray.
How It Works
Simple Explanation
Semax is derived from a brain hormone (ACTH) and increases BDNF, which helps neurons grow and connect. It also modulates dopamine and serotonin for improved mood and focus.
🔬 Technical Details (Click to expand)
As a synthetic ACTH(4-10) analog, Semax increases BDNF and NGF expression, modulates dopaminergic and serotonergic systems, and has neuroprotective effects via reduced oxidative stress and inflammation.
Key Research
BDNF Increase
Significant elevation in brain-derived neurotrophic factor
Stroke Recovery
Used clinically in Russia for stroke rehabilitation
Cognitive Enhancement
Improved memory and attention in clinical studies
Benefits
- Enhanced focus and concentration
- Increased BDNF for brain health
- May help with anxiety
- Neuroprotective effects
- Non-stimulant cognitive boost
Side Effects
- Nasal irritation — OccasionalWith nasal spray
- Headache — Rare
- Dizziness — Rare
Typical Dosing
Standard Dose
200-600mcg nasal spray, 1-2x daily
Forms Available
- • Nasal spray (most common)
- • Subcutaneous injection
Frequency
1-2x daily, cycles of 2-3 weeks
⚠️ This is general information only. Always consult a healthcare provider before starting any peptide.
Who It's For
- ✓ Those seeking non-stimulant focus
- ✓ People interested in neuroprotection
- ✓ Anyone wanting to boost BDNF
- ✓ Biohackers exploring nootropics
Who Should Avoid
- ✗ Those with nasal issues (for spray form)
- ✗ People on MAO inhibitors
- ✗ Those expecting stimulant-like effects
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