Quick Take
Ipamorelin is considered one of the 'cleanest' growth hormone secretagogues. It stimulates GH release without spiking cortisol or prolactin like older peptides. Popular for sleep, recovery, and anti-aging benefits.
How It Works
Simple Explanation
Ipamorelin mimics ghrelin and tells your pituitary gland to release growth hormone. Unlike older GH peptides, it's selective — boosting GH without messing with other hormones.
🔬 Technical Details (Click to expand)
As a selective ghrelin/GHS-R agonist, ipamorelin stimulates pulsatile GH release from the anterior pituitary. It has minimal effect on cortisol, ACTH, and prolactin levels, making it cleaner than GHRP-6 or GHRP-2.
Key Research
GH Release
Dose-dependent increase in GH without cortisol elevation
Bone Density
Improved bone mineral density in animal studies
Body Composition
Favorable changes in fat mass and lean mass
Benefits
- Cleaner GH release than older peptides
- Improved sleep quality
- Better recovery from training
- Potential anti-aging benefits
- Doesn't significantly raise cortisol
Side Effects
- Water retention — OccasionalCommon with GH increase
- Tingling/numbness — Occasional
- Hunger increase — OccasionalLess than GHRP-6
Typical Dosing
Standard Dose
200-300mcg 2-3x daily
Forms Available
- • Subcutaneous injection
Frequency
2-3x daily, often before bed and/or fasted morning
⚠️ This is general information only. Always consult a healthcare provider before starting any peptide.
Who It's For
- ✓ Those seeking GH benefits without harsh sides
- ✓ People optimizing sleep and recovery
- ✓ Anti-aging focused biohackers
- ✓ Athletes wanting cleaner options
Who Should Avoid
- ✗ Those with active cancer
- ✗ People with pituitary disorders
- ✗ Competitive athletes (banned substance)
- ✗ Pregnant or nursing women
Want the Full Protocol Guide?
Get our comprehensive guide with dosing protocols, stacking strategies, and more.