Quick Take
GHK-Cu is a naturally occurring copper peptide that declines with age. It's a powerhouse for skin health — boosting collagen, reducing wrinkles, and promoting wound healing. Unlike most peptides, it's available in cosmetic products.
How It Works
Simple Explanation
GHK-Cu delivers copper to cells and activates genes involved in tissue repair. It increases collagen and elastin production, reduces inflammation, and helps remodel damaged tissue.
🔬 Technical Details (Click to expand)
The tripeptide GHK binds copper(II) with high affinity, delivering it to tissues. It modulates expression of over 4,000 genes, including those for collagen synthesis, antioxidant enzymes, and tissue remodeling. Activates stem cells and DNA repair mechanisms.
Key Research
Collagen Synthesis
Significantly increased collagen production in skin fibroblasts
Wound Healing
Accelerated wound closure and reduced scarring
Gene Expression
Modulates 4,000+ genes toward a younger expression pattern
Benefits
- Increased collagen and elastin
- Reduced fine lines and wrinkles
- Improved skin firmness and elasticity
- Accelerated wound healing
- Hair growth stimulation
Side Effects
- Skin irritation (topical) — OccasionalStart with lower concentration
- Redness — Occasional
- Injection site reactions — OccasionalIf using injectable
Typical Dosing
Standard Dose
Topical: 1-2% creams/serums. Injectable: 1-2mg daily
Forms Available
- • Topical creams and serums (most common)
- • Subcutaneous injection
- • Microneedling combination
Frequency
Topical: 1-2x daily. Injectable: Daily for cycles
⚠️ This is general information only. Always consult a healthcare provider before starting any peptide.
Who It's For
- ✓ Anyone seeking anti-aging benefits
- ✓ People with skin damage or scars
- ✓ Those wanting non-invasive skin improvement
- ✓ Biohackers interested in longevity
Who Should Avoid
- ✗ Those with copper sensitivity
- ✗ People with Wilson's disease
- ✗ Anyone allergic to peptide cosmetics
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